Pharmacogenomics (PGx)


 

Pharmacogenomics is the study of genetic variations that influence an individual’s response to drugs. A person may respond very differently than others to the same medication. For example, two people may be taking the same dosage of the same medication, yet one person’s risk for an adverse drug event can be far greater if their genetic makeup impacts metabolism of this particular drug. Similarly, it may require one person a much greater dose of a medication to achieve a therapeutic response – the ideal medications and doses a person should be taken can be determined through genetic testing instead of trial and error. 

What Can This Test Tell Me?

This test may provide you with a clear report of the medications best suited to you.

It breaks down over 200 common medications into three categories - drugs that can be used as normal, drugs that should be used with caution, and drugs that should be discontinued.

We provide details of how your genetic makeup affects each medication, and the report breaks down and assesses your current medication/vitamin regime.

This report is best interpreted by a genetic counselor and a physician in order to provide the best care and insight into your health.

Two Ways to Get Tested:

 

Option 1: Online Purchase

Step 1: You purchase your test online, and a collection kit is sent to your home. No medical necessity is required!

Step 2: You collect your test kit according to instructions and ship the sample back to the lab using a pre-paid label.

Step 3: Within 2-3 weeks, testing is completed, reviewed by our clinical team, and a report is electronically sent back to you.

Step 4: You schedule your pre-paid session with a genetic counselor to discuss your results.

Option 2: Bill Insurance

Step 1: Your physician orders a test based on medical necessity, and your cheek swab is collected.

Step 2: Our billing team verifies coverage and begins testing if approved. If coverage is denied, we contact you to discuss options.

Step 3: Within 2-3 weeks, testing is completed, reviewed by our clinical team, and a report is electronically sent back to your doctor.

Step 4: Your doctor reviews the report with you, and you may discuss results with a genetic counselor!

 

Cost and Coverage:

For individuals ordering their own tests: Contact the office for pricing

Includes collection kit, return shipping, and genetic counseling voucher.

Billing through insurance: a doctor's order with medical necessity for testing is required to bill insurance. Our in-house billing team is happy to answer your questions!

 

Who Should Have PGx Testing?

Individuals taking multiple medications, those who are have a history of medication non-compliance, and those with a history of adverse drug events are the best candidates for PGx testing. 

 

Genes Tested:

 

Custom panels are available upon request. Please submit your custom panel inquiry below!

Inquire Here

LVG offers five PGx panels:

Comprehensive:

APOE, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, F2, F5, MTHFR, SLCO1B1, VKORC1

Cardiology & Thrombosis:

APOE, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, F2, F5, MTHFR, SLCO1B1, VKORC1

Psychiatry:

COMT, CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5

Pain:
COMT, CYP1A2, CYP2B6, CYP2C19, CYP2D6, CYP2C9, CYP3A4, CYP3A5, OPRM1

Rheumatology:

APOE, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, F2, F5, MTHFR, SLCO1B1, TPMT, VKORC1

 

Location

Lehigh Valley Genomics
2550 Brodhead Road, Suite 202
Bethlehem, PA 19047
Phone: 267-296-1325
Fax: 484-895-3719

Office Hours

Get in touch

267-296-1325